Our Platform
Our Platform: Panx1 Channel Blockers
Pannex Therapeutics has a proprietary platform to discover and develop best-in-class Panx1 channel blockers.
A Comprehensive Platform for Panx1 Blocker Innovation
Our integrated platform combines deep biology, advanced discovery technologies, medicinal chemistry excellence, and translational validation to create differentiated Panx1 channel blockers.
Deep Biology Foundation
Panx1 is a validated upstream target in chronic neuropathic pain and neuroinflammation.
Proprietary Discovery Engine
Structure-enabled discovery using the 3D human Panx1 channel and in-silico design.
Medicinal Chemistry Excellence
Hundreds of molecules designed across multiple chemical classes to optimize drug-like properties.
Translational Drug Development
Integrated research connecting biology, pharmacology and preclinical validation.
Integrated Validation
In vitro, ex vivo and in vivo validation within a development-focused framework.
Scalable & Differentiated Platform
Built to deliver differentiated clinical candidates and expand into multiple disease areas.
A Scalable Engine for Innovation
Designed to deliver differentiated clinical candidates and expand into multiple disease areas with precision and efficiency.